Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Denver and San Francisco?

The flight from Denver to San Francisco has a duration of 3h 26m.

What are the cheapest flights from Denver to San Francisco?

The cheapest one-way flight costs £117 flying with Southwest Airlines and the cheapest return flight costs £204 with Southwest Airlines.

How many airports are there in the city of Denver?

Denver has 1 airport: Denver International Airport.

How many airports does San Francisco have?

There are 2 airports in San Francisco: San Francisco International Airport, Oakland International Airport

Which San Francisco airport is the most central?

The most central airport is San Francisco International Airport, 17.9km.

Which airlines have flights from Denver to San Francisco?

There are 4 airlines with flights from Denver to San Francisco; Those that offer lower prices are JetBlue Airways (£581).

Schedules of the first and last flight from Denver to San Francisco

The first flight from Denver to San Francisco is at 10:13 and the last flight departs at 10:38.

Cheap flights from Denver to San Francisco

Fly smart, spend less

Flights to San Francisco from Denver

Cheap flights from Denver to San Francisco from £117. Denver (United States) - San Francisco (United States) return flights from £204. From 16/10/2026 (Friday) - 19/10/2026 (Monday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Denver to San Francisco

Cheapest round-trip flights from Denver to San Francisco

20 Nov - 23 Nov • 3 nights
23:59DEN
25h 59m1 stop
00:58SFO
JetBlue Airways
06:00SFO
16h 9m1 stop
23:09DEN
JetBlue Airways
from£544
20 Nov - 23 Nov • 3 nights
23:59DEN
25h 56m1 stop
00:55SFO
JetBlue Airways
06:00SFO
16h 9m1 stop
23:09DEN
JetBlue Airways
from£557
20 Nov - 23 Nov • 3 nights
23:59DEN
25h 59m1 stop
00:58SFO
JetBlue Airways
07:00SFO
15h 9m1 stop
23:09DEN
JetBlue Airways
from£565
20 Nov - 23 Nov • 3 nights
23:59DEN
23h 46m1 stop
22:45SFO
JetBlue Airways
06:00SFO
16h 9m1 stop
23:09DEN
JetBlue Airways
from£570
20 Nov - 23 Nov • 3 nights
23:59DEN
22h 22m1 stop
21:21SFO
JetBlue Airways
06:00SFO
16h 9m1 stop
23:09DEN
JetBlue Airways
from£570
20 Nov - 23 Nov • 3 nights
23:59DEN
25h 56m1 stop
00:55SFO
JetBlue Airways
07:00SFO
15h 9m1 stop
23:09DEN
JetBlue Airways
from£578

Explore all offers

Flights from Denver to San Francisco one way

Find one-way flights from Denver to San Francisco at great prices.

Explore all offers

Flights to San Francisco with top airlines

Alaska Airlines
Frontier Airlines
United Airlines
Southwest AirlinesCheapest
from £203.99

Denver to San Francisco flight information

DEPARTING FROM:

Denver International Airport

ARRIVING IN:

San Francisco International Airport, more

AIRLINES:

Alaska Airlines, Frontier Airlines, more

AVG FLIGHT TIME:

3h 26m

More information about flights to San Francisco from Denver

Information about flights from Denver to San Francisco

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

If you don’t know where to go on holiday, why not let yourself be guided by our cheap flight deals to San Francisco from Denver. Without the stress of having set dates, the search results will help you make up your mind.

Explore the additional services available on lastminute.com even once you have booked your flight Denver-San Francisco . On lastminute.com, as well as your flight Denver-San Francisco, you can also book car hire, ready for you on arrival in San Francisco. If you want to stay in San Francisco, our website has also created a way for you to book a hotel room in San Francisco with no fuss.

Low cost flights to San Francisco from Denver are not always easy to find. lastminute.com wants to make it easy for you to find a inexpensive option, so with us you can even choose flights with different airlines and save money on your next trip .

Looking for low cost flights from Denver to San Francisco ? Then look no further… lastminute.com searches all available flights from Denver to San Francisco from amongst the top low cost and scheduled airlines.

FAQs Denver to San Francisco flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Denver and San Francisco?
The flight from Denver to San Francisco has a duration of 3h 26m.
What are the cheapest flights from Denver to San Francisco?
The cheapest one-way flight costs £117 flying with Southwest Airlines and the cheapest return flight costs £204 with Southwest Airlines.
How many airports are there in the city of Denver?
Denver has 1 airport: Denver International Airport.
How many airports does San Francisco have?
There are 2 airports in San Francisco: San Francisco International Airport, Oakland International Airport
Which San Francisco airport is the most central?
The most central airport is San Francisco International Airport, 17.9km.
Which airlines have flights from Denver to San Francisco?
There are 4 airlines with flights from Denver to San Francisco; Those that offer lower prices are JetBlue Airways (£581).
Schedules of the first and last flight from Denver to San Francisco
The first flight from Denver to San Francisco is at 10:13 and the last flight departs at 10:38.