Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

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How long does a flight take between San Diego and San Francisco?

The flight from San Diego to San Francisco has a duration of 1h 27m.

What are the cheapest flights from San Diego to San Francisco?

The cheapest one-way flight costs £485 flying with JetBlue Airways and the cheapest return flight costs £118 with Southwest Airlines.

How many airports are there in the city of San Diego?

San Diego has 2 airport: San Diego International Airport, Tijuana International Airport.

How many airports does San Francisco have?

There are 2 airports in San Francisco: San Francisco International Airport, Oakland International Airport

Which San Francisco airport is the most central?

The most central airport is San Francisco International Airport, 17.9km.

Which airlines have flights from San Diego to San Francisco?

There are 2 airlines with flights from San Diego to San Francisco; Those that offer lower prices are JetBlue Airways (£549).

Schedules of the first and last flight from San Diego to San Francisco

The first flight from San Diego to San Francisco is at 00:31 and the last flight departs at 11:20.

Cheap flights from San Diego to San Francisco

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Flights to San Francisco from San Diego

Cheap flights from San Diego to San Francisco from £485. San Diego (United States) - San Francisco (United States) return flights from £118. From 30/07/2026 (Thursday) - 03/08/2026 (Monday). Check for the dates with the lowest prices and find the cheapest rates.

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Cheap flights from San Diego to San Francisco

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Flights to San Francisco from San Diego

Direct flights from San Diego to San Francisco

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San Diego to San Francisco flight information

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Information about flights from San Diego to San Francisco