Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Denver and San Diego?

The flight from Denver to San Diego has a duration of 2h 45m.

What are the cheapest flights from Denver to San Diego?

The cheapest one-way flight costs £342 flying with JetBlue Airways and the cheapest return flight costs £212 with Southwest Airlines.

How many airports are there in the city of Denver?

Denver has 1 airport: Denver International Airport.

How many airports does San Diego have?

There are 1 airports in San Diego: San Diego International Airport

Which San Diego airport is the most central?

The most central airport is San Diego International Airport, 3.9km.

Which airlines have flights from Denver to San Diego?

There are 6 airlines with flights from Denver to San Diego; Those that offer lower prices are JetBlue Airways (£597).

Schedules of the first and last flight from Denver to San Diego

The first flight from Denver to San Diego is at 09:08 and the last flight departs at 09:08.

Cheap flights from Denver to San Diego

Fly smart, spend less

Flights to San Diego from Denver

Cheap flights from Denver to San Diego from £342. Denver (United States) - San Diego (United States) return flights from £212. From 24/10/2026 (Saturday) - 25/10/2026 (Sunday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Denver to San Diego

Cheapest round-trip flights from Denver to San Diego

05 Nov - 08 Nov • 3 nights
20:50DEN
2h 30mDirect
22:20SAN
Southwest Airlines
20:00SAN
2h 25mDirect
23:25DEN
Southwest Airlines
from£226
05 Nov - 08 Nov • 3 nights
07:15DEN
2h 30mDirect
08:45SAN
Southwest Airlines
20:00SAN
2h 25mDirect
23:25DEN
Southwest Airlines
from£226
05 Nov - 08 Nov • 3 nights
20:50DEN
2h 30mDirect
22:20SAN
Southwest Airlines
17:25SAN
2h 20mDirect
20:45DEN
Southwest Airlines
from£233
05 Nov - 08 Nov • 3 nights
07:15DEN
2h 30mDirect
08:45SAN
Southwest Airlines
17:25SAN
2h 20mDirect
20:45DEN
Southwest Airlines
from£233
05 Nov - 08 Nov • 3 nights
07:15DEN
2h 30mDirect
08:45SAN
Southwest Airlines
06:15SAN
2h 30mDirect
09:45DEN
Southwest Airlines
from£233
05 Nov - 08 Nov • 3 nights
20:50DEN
2h 30mDirect
22:20SAN
Southwest Airlines
06:15SAN
2h 30mDirect
09:45DEN
Southwest Airlines
from£233

Explore all offers

Direct flights from Denver to San Diego

Book direct flights from Denver to San Diego for a smooth journey.

Explore all offers

Flights from Denver to San Diego one way

Find one-way flights from Denver to San Diego at great prices.

Explore all offers

Southwest Airlines flights from Denver to San Diego

Fly with Southwest Airlines from Denver to San Diego for less.

Explore all offers

Denver to San Diego flight information

DEPARTING FROM:

Denver International Airport

ARRIVING IN:

San Diego International Airport

AIRLINES:

Alaska Airlines, Frontier Airlines, more

AVG FLIGHT TIME:

2h 45m

More information about flights to San Diego from Denver

Information about flights from Denver to San Diego

Greetings! Welcome to the lastminute.com’s travel website for low cost flights. If you are looking for a low cost flight Denver-San Diego , you are in the right place! Your are click away from confirming your flight Denver-San Diego.

If you don’t know where to go on holiday, why not let yourself be guided by our cheap flight deals to San Diego from Denver. Without the stress of having set dates, the search results will help you make up your mind.

Once your flight Denver-San Diego is booked, using lastminute.com you can even organise the rest of your trip. From car hire and accommodation in San Diego as well as a guide to San Diego so you know in advance what there is to see and do.

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

lastminute.com cares about its customers and offers more than an online travel booking tool. We support our customers from start to finish and beyond. Helping you plan your trip, to during your holiday and even when you return from your trip .

FAQs Denver to San Diego flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Denver and San Diego?
The flight from Denver to San Diego has a duration of 2h 45m.
What are the cheapest flights from Denver to San Diego?
The cheapest one-way flight costs £342 flying with JetBlue Airways and the cheapest return flight costs £212 with Southwest Airlines.
How many airports are there in the city of Denver?
Denver has 1 airport: Denver International Airport.
How many airports does San Diego have?
There are 1 airports in San Diego: San Diego International Airport
Which San Diego airport is the most central?
The most central airport is San Diego International Airport, 3.9km.
Which airlines have flights from Denver to San Diego?
There are 6 airlines with flights from Denver to San Diego; Those that offer lower prices are JetBlue Airways (£597).
Schedules of the first and last flight from Denver to San Diego
The first flight from Denver to San Diego is at 09:08 and the last flight departs at 09:08.