Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

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How long does a flight take between New York - Manhattan and San Diego?

The flight from New York - Manhattan to San Diego has a duration of 7h 46m.

How many airports are there in the city of New York - Manhattan?

New York - Manhattan has 4 airport: NYC - All airports, Newark Liberty International Airport, John F. Kennedy International Airport, LaGuardia Airport.

How many airports does San Diego have?

There are 2 airports in San Diego: San Diego International Airport, Tijuana International Airport

Which San Diego airport is the most central?

The most central airport is San Diego International Airport, 3.9km.

Which airlines have flights from New York - Manhattan to San Diego?

There are 5 airlines with flights from New York - Manhattan to San Diego; Those that offer lower prices are JetBlue Airways (£283).

Schedules of the first and last flight from New York - Manhattan to San Diego

The first flight from New York - Manhattan to San Diego is at 10:04 and the last flight departs at 19:02.

Cheap flights from New York - Manhattan to San Diego

Fly smart, spend less

Flights to San Diego from New York - Manhattan

Cheap flights from New York - Manhattan to San Diego from £127. New York - Manhattan (United States) - San Diego (United States) return flights from £295. From 01/10/2026 (Thursday) - 07/10/2026 (Wednesday). Check for the dates with the lowest prices and find the cheapest rates.

Direct flights from New York - Manhattan to San Diego

Book direct flights from New York - Manhattan to San Diego for a smooth journey.

19 Aug - 23 Aug • 4 nights

05 Aug - 10 Aug • 5 nights

21 Aug - 24 Aug • 3 nights

13 Jul - 23 Jul • 10 nights

08 Jul - 12 Jul • 4 nights

20 Jul - 22 Jul • 2 nights

Flights from New York - Manhattan to San Diego one way

Find one-way flights from New York - Manhattan to San Diego at great prices.

25 Aug

28 Aug

08 Sept

11 Sept

12 Sept

14 Aug

Cheapest flights from New York - Manhattan to San Diego

Get the cheapest flights from New York - Manhattan to San Diego today.

19 Aug - 23 Aug • 4 nights

10 Aug - 12 Aug • 2 nights

05 Aug - 10 Aug • 5 nights

21 Aug - 24 Aug • 3 nights

08 Jul - 12 Jul • 4 nights

10 Aug - 12 Aug • 2 nights

Cheap flights from Newark Liberty International Airport to San Diego

Find cheap flights from Newark Liberty International Airport to San Diego now.

19 Aug - 23 Aug • 4 nights

13 Jul - 23 Jul • 10 nights

10 Aug - 12 Aug • 2 nights

08 Jul - 12 Jul • 4 nights

20 Jul - 22 Jul • 2 nights

24 Jun - 28 Jun • 4 nights

Cheap flights from John F. Kennedy International Airport to San Diego

Find cheap flights from John F. Kennedy International Airport to San Diego now.

19 Aug - 23 Aug • 4 nights

05 Aug - 10 Aug • 5 nights

21 Aug - 24 Aug • 3 nights

13 Jul - 23 Jul • 10 nights

08 Jul - 12 Jul • 4 nights

20 Jul - 22 Jul • 2 nights

Cheap flights from LaGuardia Airport to San Diego

Find cheap flights from LaGuardia Airport to San Diego now.

10 Aug - 12 Aug • 2 nights

08 Jul - 12 Jul • 4 nights

New York - Manhattan to San Diego flight information

DEPARTING FROM:

LaGuardia Airport, more

ARRIVING IN:

San Diego International Airport, more

AIRLINES:

American Airlines, Delta Air Lines, JetBlue Airways, more

AVG FLIGHT TIME:

7h 46m

More information about flights to San Diego from New York - Manhattan

Information about flights from New York to San Diego

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Explore the additional services available on lastminute.com even once you have booked your flight New York-San Diego . On lastminute.com, as well as your flight New York-San Diego, you can also book car hire, ready for you on arrival in San Diego. If you want to stay in San Diego, our website has also created a way for you to book a hotel room in San Diego with no fuss.

FAQs New York - Manhattan to San Diego flights

FAQs

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

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Cheap flights from New York - Manhattan to San Diego

Fly smart, spend less

Flights to San Diego from New York - Manhattan

Direct flights from New York - Manhattan to San Diego

Flights from New York - Manhattan to San Diego one way

Cheapest flights from New York - Manhattan to San Diego

Cheap flights from Newark Liberty International Airport to San Diego

Cheap flights from John F. Kennedy International Airport to San Diego

Cheap flights from LaGuardia Airport to San Diego

Flights to San Diego with top airlines

New York - Manhattan to San Diego flight information

More information about flights to San Diego from New York - Manhattan

Information about flights from New York to San Diego

FAQs New York - Manhattan to San Diego flights

FAQs

Can I combine different airlines on the same trip?

Is lastminute.com a trustworthy travel brand?

What options are there if I have to change my flight?

I am afraid to lose my luggage, every time I fly. What can I do?

How long does a flight take between New York - Manhattan and San Diego?

What are the cheapest flights from New York - Manhattan to San Diego?

How many airports are there in the city of New York - Manhattan?

How many airports does San Diego have?

Which San Diego airport is the most central?

Which airlines have flights from New York - Manhattan to San Diego?

Schedules of the first and last flight from New York - Manhattan to San Diego