Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between San Francisco and San Diego?

The flight from San Francisco to San Diego has a duration of 1h 50m.

What are the cheapest flights from San Francisco to San Diego?

The cheapest one-way flight costs £120 flying with Southwest Airlines and the cheapest return flight costs £202 with Southwest Airlines.

How many airports are there in the city of San Francisco?

San Francisco has 2 airport: San Francisco International Airport, Oakland International Airport.

How many airports does San Diego have?

There are 1 airports in San Diego: San Diego International Airport

Which San Diego airport is the most central?

The most central airport is San Diego International Airport, 3.9km.

Which airlines have flights from San Francisco to San Diego?

There are 4 airlines with flights from San Francisco to San Diego; Those that offer lower prices are Southwest Airlines (£196).

Schedules of the first and last flight from San Francisco to San Diego

The first flight from San Francisco to San Diego is at 17:00 and the last flight departs at 17:00.

Cheap flights from San Francisco to San Diego

Fly smart, spend less

Flights to San Diego from San Francisco

Cheap flights from San Francisco to San Diego from £120. San Francisco (United States) - San Diego (United States) return flights from £202. From 26/12/2026 (Saturday) - 27/12/2026 (Sunday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from San Francisco to San Diego

Cheapest round-trip flights from San Francisco to San Diego

05 Nov - 09 Nov • 4 nights
06:50SFO
1h 35mDirect
08:25SAN
Southwest Airlines
17:25SAN
1h 40mDirect
19:05SFO
Southwest Airlines
from£118
05 Nov - 09 Nov • 4 nights
06:50SFO
1h 35mDirect
08:25SAN
Southwest Airlines
18:35SAN
1h 40mDirect
20:15SFO
Southwest Airlines
from£118
05 Nov - 09 Nov • 4 nights
06:50SFO
1h 35mDirect
08:25SAN
Southwest Airlines
15:05SAN
1h 45mDirect
16:50SFO
Southwest Airlines
from£118
05 Nov - 09 Nov • 4 nights
18:30SFO
1h 40mDirect
20:10SAN
Southwest Airlines
18:35SAN
1h 40mDirect
20:15SFO
Southwest Airlines
from£118
05 Dec - 07 Dec • 2 nights
06:30SFO
1h 35mDirect
08:05SAN
Southwest Airlines
16:30SAN
1h 40mDirect
18:10SFO
Southwest Airlines
from£118
05 Dec - 07 Dec • 2 nights
06:30SFO
1h 35mDirect
08:05SAN
Southwest Airlines
18:30SAN
1h 40mDirect
20:10SFO
Southwest Airlines
from£118

Explore all offers

Direct flights from San Francisco to San Diego

Book direct flights from San Francisco to San Diego for a smooth journey.

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Flights from San Francisco to San Diego one way

Find one-way flights from San Francisco to San Diego at great prices.

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Cheap flights from San Francisco International Airport to San Diego

Find cheap flights from San Francisco International Airport to San Diego now.

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Southwest Airlines flights from San Francisco to San Diego

Fly with Southwest Airlines from San Francisco to San Diego for less.

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San Francisco to San Diego flight information

DEPARTING FROM:

San Francisco International Airport, more

ARRIVING IN:

San Diego International Airport

AIRLINES:

Alaska Airlines, Frontier Airlines, more

AVG FLIGHT TIME:

1h 50m

More information about flights to San Diego from San Francisco

Good to know

Information about flights from San Francisco to San Diego

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

As well as your flight from San Francisco to San Diego , guess what, it’s also really easy with lastminute.com to have a car waiting for you when you arrive as well as accommodation in San Diego.

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from San Francisco to San Diego , all you have to do is complete the search form and in no time you will be flying off to San Diego.

If you don’t know where to go on holiday, why not let yourself be guided by our cheap flight deals to San Diego from San Francisco. Without the stress of having set dates, the search results will help you make up your mind.

Need inspiration for your next holiday? Join lastminute.com’s facebook page and be sure to get top travel tips for your next trip .

FAQs San Francisco to San Diego flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between San Francisco and San Diego?
The flight from San Francisco to San Diego has a duration of 1h 50m.
What are the cheapest flights from San Francisco to San Diego?
The cheapest one-way flight costs £120 flying with Southwest Airlines and the cheapest return flight costs £202 with Southwest Airlines.
How many airports are there in the city of San Francisco?
San Francisco has 2 airport: San Francisco International Airport, Oakland International Airport.
How many airports does San Diego have?
There are 1 airports in San Diego: San Diego International Airport
Which San Diego airport is the most central?
The most central airport is San Diego International Airport, 3.9km.
Which airlines have flights from San Francisco to San Diego?
There are 4 airlines with flights from San Francisco to San Diego; Those that offer lower prices are Southwest Airlines (£196).
Schedules of the first and last flight from San Francisco to San Diego
The first flight from San Francisco to San Diego is at 17:00 and the last flight departs at 17:00.