Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Chicago and Manchester?

The flight from Chicago to Manchester has a duration of 10h 23m.

What are the cheapest flights from Chicago to Manchester?

The cheapest one-way flight costs £227 flying with Icelandair and the cheapest return flight costs £580 with Icelandair.

How many airports are there in the city of Chicago?

Chicago has 2 airport: CHI - All airports, Chicago O'Hare International Airport.

How many airports does Manchester have?

There are 1 airports in Manchester: Manchester Airport

Which Manchester airport is the most central?

The most central airport is Manchester Airport, 13.1km.

Schedules of the first and last flight from Chicago to Manchester

The first flight from Chicago to Manchester is at 09:00 and the last flight departs at 19:20.

Cheap flights from Chicago to Manchester

Fly smart, spend less

Flights to Manchester from Chicago

Cheap flights from Chicago to Manchester from £227. Chicago (United States) - Manchester (United Kingdom) return flights from £580. From 24/09/2026 (Thursday) - 30/09/2026 (Wednesday). Check for the dates with the lowest prices and find the cheapest rates.

Flights from Chicago to Manchester one way

Find one-way flights from Chicago to Manchester at great prices.

04 Aug

02 Aug

19 Sept

21 Sept

01 Aug

22 Aug

Cheapest flights from Chicago to Manchester

Get the cheapest flights from Chicago to Manchester today.

21 Sept - 25 Sept • 4 nights

17:10ORD

10h 50m1 stop

10:00MAN

Virgin Atlantic Airways

14:55MAN

12h 42m1 stop

21:37ORD

Virgin Atlantic Airways

from£674

03 Aug - 09 Aug • 6 nights

13 Jul - 23 Jul • 10 nights

13:00ORD

13h 15m1 stop

08:15MAN

Virgin Atlantic Airways

20:50MAN

23h 25m1 stop

14:15ORD

Virgin Atlantic Airways

from£889

13 Jul - 23 Jul • 10 nights

12:41MDW

14h 9m1 stop

08:50MAN

Virgin Atlantic Airways

08:55MAN

11h 20m1 stop

14:15MDW

Virgin Atlantic Airways

from£957

Explore all offers

Cheap flights from Chicago O'Hare International Airport to Manchester

Find cheap flights from Chicago O'Hare International Airport to Manchester now.

21 Sept - 25 Sept • 4 nights

17:10ORD

10h 50m1 stop

10:00MAN

Virgin Atlantic Airways

14:55MAN

12h 42m1 stop

21:37ORD

Virgin Atlantic Airways

from£674

03 Aug - 09 Aug • 6 nights

13 Jul - 23 Jul • 10 nights

More information about flights to Manchester from Chicago

Information about flights from Chicago to Manchester

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Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Chicago to Manchester , all you have to do is complete the search form and in no time you will be flying off to Manchester.

FAQs Chicago to Manchester flights

FAQs

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

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