Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between San Francisco and Mexico City?

The flight from San Francisco to Mexico City has a duration of 5h 24m.

What are the cheapest flights from San Francisco to Mexico City?

The cheapest one-way flight costs £122 flying with Volaris and the cheapest return flight costs £264 with Volaris.

How many airports are there in the city of San Francisco?

San Francisco has 2 airport: San Francisco International Airport, Oakland International Airport.

How many airports does Mexico City have?

There are 1 airports in Mexico City: Mexico City (MEX Airport)

Which Mexico City airport is the most central?

The most central airport is Mexico City (MEX Airport), 5.2km.

Cheap flights from San Francisco to Mexico City

Fly smart, spend less

Flights to Mexico City from San Francisco

Cheap flights from San Francisco to Mexico City from £122. San Francisco (United States) - Mexico City (Mexico) return flights from £264. From 03/11/2026 (Tuesday) - 10/11/2026 (Tuesday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from San Francisco to Mexico City

Cheapest round-trip flights from San Francisco to Mexico City

03 Oct - 09 Oct • 6 nights
23:55SFO
4h 35mDirect
05:30MEX
Aeromexico
17:15MEX
4h 55mDirect
21:10SFO
Aeromexico
from£415
03 Oct - 09 Oct • 6 nights
23:30SFO
9h 25m1 stop
09:55MEX
Aeromexico
17:15MEX
4h 55mDirect
21:10SFO
Aeromexico
from£415
03 Oct - 09 Oct • 6 nights
23:55SFO
4h 35mDirect
05:30MEX
Aeromexico
15:10MEX
7h 40m1 stop
21:50SFO
Aeromexico
from£419
03 Oct - 09 Oct • 6 nights
23:55SFO
4h 35mDirect
05:30MEX
Aeromexico
11:10MEX
11h 45m1 stop
21:55SFO
Aeromexico
from£419
03 Oct - 09 Oct • 6 nights
23:55SFO
4h 35mDirect
05:30MEX
Aeromexico
09:25MEX
4h 55mDirect
13:20SFO
Aeromexico
from£452
01 Nov - 08 Nov • 7 nights
22:23SFO
4h 27mDirect
04:50MEX
Aeromexico
08:40MEX
4h 58mDirect
11:38SFO
Aeromexico
from£525

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Direct flights from San Francisco to Mexico City

Book direct flights from San Francisco to Mexico City for a smooth journey.

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Flights from San Francisco to Mexico City one way

Find one-way flights from San Francisco to Mexico City at great prices.

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Cheap flights from San Francisco International Airport to Mexico City

Find cheap flights from San Francisco International Airport to Mexico City now.

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Cheap flights from Oakland International Airport to Mexico City

Find cheap flights from Oakland International Airport to Mexico City now.

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Aeromexico flights from San Francisco to Mexico City

Fly with Aeromexico from San Francisco to Mexico City for less.

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San Francisco to Mexico City flight information

DEPARTING FROM:

San Francisco International Airport, more

ARRIVING IN:

Mexico City (MEX Airport)

AIRLINES:

Aeromexico, United Airlines, Volaris

AVG FLIGHT TIME:

5h 24m

More information about flights to Mexico City from San Francisco

Information about flights from San Francisco to Mexico City

If you don’t know where to go on holiday, why not let yourself be guided by our cheap flight deals to Mexico City from San Francisco. Without the stress of having set dates, the search results will help you make up your mind.

lastminute.com App for iPhone and Android – the solution to your travelling needs. Perfect if you are always on the move, need to book your travel from anywhere quickly and easily. Take this practical and reliable tool with you on your travels .

Join lastminute.com’s facebook page and be informed on the latest travel giveaways and news. Make your trip a memorable one and then tell us about it!

Greetings! Welcome to the lastminute.com’s travel website for low cost flights. If you are looking for a low cost flight San Francisco-Mexico City , you are in the right place! Your are click away from confirming your flight San Francisco-Mexico City.

Explore the additional services available on lastminute.com even once you have booked your flight San Francisco-Mexico City . On lastminute.com, as well as your flight San Francisco-Mexico City, you can also book car hire, ready for you on arrival in Mexico City. If you want to stay in Mexico City, our website has also created a way for you to book a hotel room in Mexico City with no fuss.

FAQs San Francisco to Mexico City flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between San Francisco and Mexico City?
The flight from San Francisco to Mexico City has a duration of 5h 24m.
What are the cheapest flights from San Francisco to Mexico City?
The cheapest one-way flight costs £122 flying with Volaris and the cheapest return flight costs £264 with Volaris.
How many airports are there in the city of San Francisco?
San Francisco has 2 airport: San Francisco International Airport, Oakland International Airport.
How many airports does Mexico City have?
There are 1 airports in Mexico City: Mexico City (MEX Airport)
Which Mexico City airport is the most central?
The most central airport is Mexico City (MEX Airport), 5.2km.