Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

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In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

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How long does a flight take between Rome and Prague?

The flight from Rome to Prague has a duration of 1h 54m.

What are the cheapest flights from Rome to Prague?

The cheapest one-way flight costs £40 flying with Ryanair and the cheapest return flight costs £133 with Wizz Air Malta.

How many airports are there in the city of Rome?

Rome has 3 airport: ROM - All airports, Fiumicino Airport, Rome Ciampino Airport.

How many airports does Prague have?

There are 1 airports in Prague: Vaclav Havel Airport Prague

Which Prague airport is the most central?

The most central airport is Vaclav Havel Airport Prague, 11.5km.

Which airlines have flights from Rome to Prague?

There are 5 airlines with flights from Rome to Prague; Those that offer lower prices are Wizz Air Malta (£46), Ryanair (£50), Smart Wings (£96).

Schedules of the first and last flight from Rome to Prague

The first flight from Rome to Prague is at 07:50 and the last flight departs at 19:40.

Cheap flights from Rome to Prague

Fly smart, spend less

Flights to Prague from Rome

Cheap flights from Rome to Prague from £40. Rome (Italy) - Prague (Czech Republic) return flights from £133. From 23/06/2026 (Tuesday) - 24/06/2026 (Wednesday). Check for the dates with the lowest prices and find the cheapest rates.

Direct flights from Rome to Prague

Book direct flights from Rome to Prague for a smooth journey.

09 Sept - 12 Sept • 3 nights

23 Jul - 28 Jul • 5 nights

11 Sept - 14 Sept • 3 nights

23 Jul - 28 Jul • 5 nights

10 Sept - 13 Sept • 3 nights

05 Sept - 08 Sept • 3 nights

Flights from Rome to Prague one way

Find one-way flights from Rome to Prague at great prices.

16 Sept

08 Jul

10 Jul

16 Sept

19 Sept

19 Sept

Cheapest flights from Rome to Prague

Get the cheapest flights from Rome to Prague today.

09 Sept - 12 Sept • 3 nights

23 Jul - 28 Jul • 5 nights

11 Sept - 14 Sept • 3 nights

23 Jul - 28 Jul • 5 nights

06 Sept - 09 Sept • 3 nights

10 Sept - 13 Sept • 3 nights

Cheap flights from Fiumicino Airport to Prague

Find cheap flights from Fiumicino Airport to Prague now.

11 Sept - 14 Sept • 3 nights

06 Sept - 09 Sept • 3 nights

01 Sept - 04 Sept • 3 nights

08 Sept - 11 Sept • 3 nights

09 Sept - 12 Sept • 3 nights

07 Sept - 10 Sept • 3 nights

Cheap flights from Rome Ciampino Airport to Prague

Find cheap flights from Rome Ciampino Airport to Prague now.

23 Jul - 28 Jul • 5 nights

05 Sept - 08 Sept • 3 nights

09 Sept - 12 Sept • 3 nights

08 Sept - 11 Sept • 3 nights

16 Sept - 19 Sept • 3 nights

19 Sept - 22 Sept • 3 nights

Vueling flights from Rome to Prague

Fly with Vueling from Rome to Prague for less.

16 Sept - 19 Sept • 3 nights

12 Sept - 15 Sept • 3 nights

19 Sept - 22 Sept • 3 nights

19 Sept - 22 Sept • 3 nights

06 Sept - 09 Sept • 3 nights

04 Sept - 07 Sept • 3 nights

Rome to Prague flight information

DEPARTING FROM:

ROM - All airports, Rome Ciampino Airport, Fiumicino Airport

ARRIVING IN:

Vaclav Havel Airport Prague

AIRLINES:

Czech Airlines, EasyJet, Smart Wings, Vueling, Wizzair

AVG FLIGHT TIME:

1h 54m

More information about flights to Prague from Rome

Information about flights from Rome to Prague

lastminute.com’s facebook page gives you an easy way to stay up to date with giveaways and promotions on low cost flights and holidays to Prague from Rome.

Not only can you use the lastminute.com website to search low cost flights, but we have even preselected some flight offers from Rome to Prague for you to save you time.

Once your flight Rome-Prague is booked, using lastminute.com you can even organise the rest of your trip. From car hire and accommodation in Prague as well as a guide to Prague so you know in advance what there is to see and do.

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Rome to Prague , all you have to do is complete the search form and in no time you will be flying off to Prague.

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

FAQs Rome to Prague flights

FAQs

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

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