Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

What are the cheapest flights from Prague to Istanbul?

The cheapest one-way flight costs £60 flying with AJet and the cheapest return flight costs £112 with AJet.

How many airports are there in the city of Prague?

Prague has 1 airport: Vaclav Havel Airport Prague.

How many airports does Istanbul have?

There are 1 airports in Istanbul: Istanbul Sabiha Gokcen International Airport

Which Istanbul airport is the most central?

The most central airport is Istanbul Sabiha Gokcen International Airport, 31.8km.

Cheap flights from Prague to Istanbul

Fly smart, spend less

Flights to Istanbul from Prague

Cheap flights from Prague to Istanbul from £60. Prague (Czech Republic) - Istanbul (Türkiye) return flights from £112. From 02/10/2026 (Friday) - 05/10/2026 (Monday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Prague to Istanbul

Cheapest round-trip flights from Prague to Istanbul

15 Sept - 22 Sept • 7 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
07:55SAW
2h 40mDirect
09:35PRG
AJet
from£112
15 Sept - 22 Sept • 7 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
16:40SAW
2h 40mDirect
18:20PRG
Pegasus Airlines
from£112
15 Sept - 22 Sept • 7 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
08:50SAW
2h 40mDirect
10:30PRG
Pegasus Airlines
from£112
15 Sept - 22 Sept • 7 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
13:10SAW
2h 40mDirect
14:50PRG
Pegasus Airlines
from£112
01 Oct - 04 Oct • 3 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
07:55SAW
2h 40mDirect
09:35PRG
AJet
from£112
02 Oct - 05 Oct • 3 nights
10:35PRG
2h 35mDirect
14:10SAW
AJet
07:55SAW
2h 40mDirect
09:35PRG
AJet
from£112

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Direct flights from Prague to Istanbul

Book direct flights from Prague to Istanbul for a smooth journey.

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Flights from Prague to Istanbul one way

Find one-way flights from Prague to Istanbul at great prices.

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Pegasus Airlines flights from Prague to Istanbul

Fly with Pegasus Airlines from Prague to Istanbul for less.

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More information about flights to Istanbul from Prague

Information about flights from Prague to Istanbul

lastminute.com selects from hundreds of flight deals Prague-Istanbul some of the best deals that month to save you time. Why not take advantage of the monthly flight offers and book now.

What could be easier than using lastminute.com as your one stop travel shop? With all the services you find on lastminute.com, it’s more than just flights, you can book all the travel requirements for you trips right here.

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Prague to Istanbul , all you have to do is complete the search form and in no time you will be flying off to Istanbul.

Need inspiration for your next holiday? Join lastminute.com’s facebook page and be sure to get top travel tips for your next trip .

As well as your flight from Prague to Istanbul , guess what, it’s also really easy with lastminute.com to have a car waiting for you when you arrive as well as accommodation in Istanbul.

FAQs Prague to Istanbul flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
What are the cheapest flights from Prague to Istanbul?
The cheapest one-way flight costs £60 flying with AJet and the cheapest return flight costs £112 with AJet.
How many airports are there in the city of Prague?
Prague has 1 airport: Vaclav Havel Airport Prague.
How many airports does Istanbul have?
There are 1 airports in Istanbul: Istanbul Sabiha Gokcen International Airport
Which Istanbul airport is the most central?
The most central airport is Istanbul Sabiha Gokcen International Airport, 31.8km.