Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

What are the cheapest flights from Madrid to Istanbul?

The cheapest one-way flight costs £74 flying with Pegasus Airlines and the cheapest return flight costs £131 with Pegasus Airlines.

How many airports are there in the city of Madrid?

Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.

How many airports does Istanbul have?

There are 1 airports in Istanbul: Istanbul Sabiha Gokcen International Airport

Which Istanbul airport is the most central?

The most central airport is Istanbul Sabiha Gokcen International Airport, 31.8km.

Which airlines have flights from Madrid to Istanbul?

There are 2 airlines with flights from Madrid to Istanbul; Those that offer lower prices are Pegasus Airlines (£87), Turkish Airlines (£224).

Schedules of the first and last flight from Madrid to Istanbul

The first flight from Madrid to Istanbul is at 13:00 and the last flight departs at 23:45.

Cheap flights from Madrid to Istanbul

Fly smart, spend less

Flights to Istanbul from Madrid

Cheap flights from Madrid to Istanbul from £74. Madrid (Spain) - Istanbul (Türkiye) return flights from £131. From 12/02/2027 (Friday) - 15/02/2027 (Monday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Madrid to Istanbul

Cheapest round-trip flights from Madrid to Istanbul

25 Oct - 27 Oct • 2 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
11:55SAW
4h 25mDirect
14:20MAD
Pegasus Airlines
from£131
04 Nov - 11 Nov • 7 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
11:55SAW
4h 25mDirect
14:20MAD
Pegasus Airlines
from£131
04 Nov - 11 Nov • 7 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
09:15SAW
4h 25mDirect
11:40MAD
Pegasus Airlines
from£131
05 Nov - 10 Nov • 5 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
09:15SAW
4h 25mDirect
11:40MAD
Pegasus Airlines
from£131
05 Nov - 10 Nov • 5 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
11:55SAW
4h 25mDirect
14:20MAD
Pegasus Airlines
from£131
03 Dec - 13 Dec • 10 nights
12:40MAD
4h 10mDirect
18:50SAW
Pegasus Airlines
11:55SAW
4h 25mDirect
14:20MAD
Pegasus Airlines
from£131

Explore all offers

Direct flights from Madrid to Istanbul

Book direct flights from Madrid to Istanbul for a smooth journey.

Explore all offers

Flights from Madrid to Istanbul one way

Find one-way flights from Madrid to Istanbul at great prices.

Explore all offers

Pegasus Airlines flights from Madrid to Istanbul

Fly with Pegasus Airlines from Madrid to Istanbul for less.

Explore all offers

More information about flights to Istanbul from Madrid

Information about flights from Madrid to Istanbul

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Madrid to Istanbul , all you have to do is complete the search form and in no time you will be flying off to Istanbul.

Need inspiration for your next holiday? Join lastminute.com’s facebook page and be sure to get top travel tips for your next trip .

As well as your flight from Madrid to Istanbul , guess what, it’s also really easy with lastminute.com to have a car waiting for you when you arrive as well as accommodation in Istanbul.

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

If you don’t know where to go on holiday, why not let yourself be guided by our cheap flight deals to Istanbul from Madrid. Without the stress of having set dates, the search results will help you make up your mind.

FAQs Madrid to Istanbul flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
What are the cheapest flights from Madrid to Istanbul?
The cheapest one-way flight costs £74 flying with Pegasus Airlines and the cheapest return flight costs £131 with Pegasus Airlines.
How many airports are there in the city of Madrid?
Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.
How many airports does Istanbul have?
There are 1 airports in Istanbul: Istanbul Sabiha Gokcen International Airport
Which Istanbul airport is the most central?
The most central airport is Istanbul Sabiha Gokcen International Airport, 31.8km.
Which airlines have flights from Madrid to Istanbul?
There are 2 airlines with flights from Madrid to Istanbul; Those that offer lower prices are Pegasus Airlines (£87), Turkish Airlines (£224).
Schedules of the first and last flight from Madrid to Istanbul
The first flight from Madrid to Istanbul is at 13:00 and the last flight departs at 23:45.