Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Manchester and Brussels?

The flight from Manchester to Brussels has a duration of 1h 24m.

What are the cheapest flights from Manchester to Brussels?

The cheapest one-way flight costs £34 flying with Ryanair and the cheapest return flight costs £51 with Ryanair.

How many airports are there in the city of Manchester?

Manchester has 1 airport: Manchester Airport.

How many airports does Brussels have?

There are 3 airports in Brussels: Brussels Airport, Charleroi Airport, Antwerp International Airport

Which Brussels airport is the most central?

The most central airport is Brussels Airport, 10.7km.

Which airlines have flights from Manchester to Brussels?

There are 2 airlines with flights from Manchester to Brussels; Those that offer lower prices are Ryanair (£34), Brussels Airlines (£218).

Schedules of the first and last flight from Manchester to Brussels

The first flight from Manchester to Brussels is at 08:10 and the last flight departs at 22:55.

Cheap flights from Manchester to Brussels

Fly smart, spend less

Flights to Brussels from Manchester

Cheap flights from Manchester to Brussels from £34. Manchester (United Kingdom) - Brussels (Belgium) return flights from £51. From 22/07/2026 (Wednesday) - 29/07/2026 (Wednesday). Check for the dates with the lowest prices and find the cheapest rates.

Secure payment

This website is property of BravoNext, S.A headquartered in Vicolo de' Calvi, 2, 6830, Chiasso, Switzerland (Company/VAT num. CHE-115.704.228), a company belonging to lastminute.com group. © 2026 - All rights reserved. The services provided on this website are made available by lastminute.com group and its Partners. Flight-inclusive holidays are provided by BravoNext, S.A. and are protected under ATOL licence (11082). Non-flight packages are also sold by BravoNext S.A. and are protected under ABTOT (Association of Bonded Travel Organisers Trust Limited) scheme of financial protection (5503). "lastminute.com", "lastminute", "LM", "Top Secret Hotels" and "Top Secret" are all registered trademarks owned by a company of lastminute.com group. Bravonext, S.A. is not responsible for content on external Web sites.

Cheap flights from Manchester to Brussels

Fly smart, spend less

Flights to Brussels from Manchester

Direct flights from Manchester to Brussels

Flights from Manchester to Brussels one way

Cheapest flights from Manchester to Brussels

Cheap flights from Manchester Airport to Brussels

Brussels Airlines flights from Manchester to Brussels

Flights to Brussels with top airlines

Manchester to Brussels flight information

More information about flights to Brussels from Manchester

Information about flights from Manchester to Brussels