Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Manchester and Chicago?

The flight from Manchester to Chicago has a duration of 14h 12m.

What are the cheapest flights from Manchester to Chicago?

The cheapest one-way flight costs £578 flying with Virgin Atlantic Airways and the cheapest return flight costs £628 with SAS Scandinavian Airlines.

How many airports are there in the city of Manchester?

Manchester has 1 airport: Manchester Airport.

How many airports does Chicago have?

There are 3 airports in Chicago: CHI - All airports, Chicago O'Hare International Airport, Midway International Airport

Which Chicago airport is the most central?

The most central airport is Midway International Airport, 13.6km.

Schedules of the first and last flight from Manchester to Chicago

The first flight from Manchester to Chicago is at 16:49 and the last flight departs at 19:20.

Cheap flights from Manchester to Chicago

Fly smart, spend less

Flights to Chicago from Manchester

Cheap flights from Manchester to Chicago from £578. Manchester (United Kingdom) - Chicago (United States) return flights from £628. From 21/11/2026 (Saturday) - 24/11/2026 (Tuesday). Check for the dates with the lowest prices and find the cheapest rates.

Round trip

One Way

Round-trip flights from Manchester to Chicago

Cheapest round-trip flights from Manchester to Chicago

19 Nov - 27 Nov • 8 nights
10:10MAN
12h 35m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
32h 20m
1 stop
09:30MAN
SAS Scandinavian Airlines
from£593
19 Nov - 27 Nov • 8 nights
19:15MAN
27h 30m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
32h 20m
1 stop
09:30MAN
SAS Scandinavian Airlines
from£593
26 Nov - 01 Dec • 5 nights
10:10MAN
12h 35m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
17h 25m
1 stop
18:35MAN
SAS Scandinavian Airlines
from£593
16 Jan - 23 Jan • 7 nights
10:10MAN
12h 35m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
32h 20m
1 stop
09:30MAN
SAS Scandinavian Airlines
from£610
20 Nov - 22 Nov • 2 nights
10:10MAN
12h 35m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
32h 20m
1 stop
09:30MAN
SAS Scandinavian Airlines
from£628
22 Dec - 29 Dec • 7 nights
10:10MAN
12h 35m
1 stop
16:45ORD
SAS Scandinavian Airlines
19:10ORD
32h 20m
1 stop
09:30MAN
SAS Scandinavian Airlines
from£660

Explore all offers

Flights from Manchester to Chicago one way

Find one-way flights from Manchester to Chicago at great prices.

Explore all offers

More information about flights to Chicago from Manchester

Good to know

Information about flights from Manchester to Chicago

Once your flight Manchester-Chicago is booked, using lastminute.com you can even organise the rest of your trip. From car hire and accommodation in Chicago as well as a guide to Chicago so you know in advance what there is to see and do.

lastminute.com’s facebook page gives you an easy way to stay up to date with giveaways and promotions on low cost flights and holidays to Chicago from Manchester.

Take advantage of our flight offers to Chicago from Manchester . This month’s best flight deals have been specially selected for you.

If you are a frequent traveller , download our iPhone and Android app free of charge. It will change your travelling habits and be extremely useful whilst you are away on trips.

Welcome to the lastminute.com travel website! You have arrived in the right place if you are looking for a low cost flight Manchester-Chicago . Complete the form on the flight search engine correctly, and we are sure to have what you are looking for.

FAQs Manchester to Chicago flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Manchester and Chicago?
The flight from Manchester to Chicago has a duration of 14h 12m.
What are the cheapest flights from Manchester to Chicago?
The cheapest one-way flight costs £578 flying with Virgin Atlantic Airways and the cheapest return flight costs £628 with SAS Scandinavian Airlines.
How many airports are there in the city of Manchester?
Manchester has 1 airport: Manchester Airport.
How many airports does Chicago have?
There are 3 airports in Chicago: CHI - All airports, Chicago O'Hare International Airport, Midway International Airport
Which Chicago airport is the most central?
The most central airport is Midway International Airport, 13.6km.
Schedules of the first and last flight from Manchester to Chicago
The first flight from Manchester to Chicago is at 16:49 and the last flight departs at 19:20.