Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Madrid and Santorini?

The flight from Madrid to Santorini has a duration of 3h 40m.

What are the cheapest flights from Madrid to Santorini?

The cheapest one-way flight costs £64 flying with Iberia and the cheapest return flight costs £372 with Iberia.

How many airports are there in the city of Madrid?

Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.

How many airports does Santorini have?

There are 1 airports in Santorini: Santorini International Airport

Which Santorini airport is the most central?

The most central airport is Santorini International Airport, 4.2km.

Which airlines have flights from Madrid to Santorini?

There are 1 airlines with flights from Madrid to Santorini; Those that offer lower prices are Iberia (£64).

Schedules of the first and last flight from Madrid to Santorini

The first flight from Madrid to Santorini is at 14:45 and the last flight departs at 22:50.

Cheap flights from Madrid to Santorini

Fly smart, spend less

Flights to Santorini from Madrid

Cheap flights from Madrid to Santorini from £64. Madrid (Spain) - Santorini (Greece) return flights from £372. From 12/09/2026 (Saturday) - 14/09/2026 (Monday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Madrid to Santorini

Cheapest round-trip flights from Madrid to Santorini

14 Oct - 18 Oct • 4 nights
07:00MAD
10h 20m1 stop
18:20JTR
Lufthansa
20:55JTR
13h 25m1 stop
09:20MAD
SWISS
from£214
14 Oct - 18 Oct • 4 nights
07:00MAD
10h 20m1 stop
18:20JTR
Lufthansa, Discover Airlines
20:55JTR
13h 25m1 stop
09:20MAD
SWISS
from£214
14 Oct - 18 Oct • 4 nights
05:55MAD
11h 25m2 stops
18:20JTR
Lufthansa
20:55JTR
13h 25m1 stop
09:20MAD
SWISS
from£253
14 Oct - 18 Oct • 4 nights
05:55MAD
11h 25m2 stops
18:20JTR
Lufthansa, Discover Airlines
20:55JTR
13h 25m1 stop
09:20MAD
SWISS
from£253
12 Nov - 15 Nov • 3 nights
14:20MAD
5h 50m1 stop
21:10JTR
Sky Express
21:35JTR
16h 45m1 stop
13:20MAD
Sky Express
from£272
08 Oct - 12 Oct • 4 nights
08:20MAD
7h 35m1 stop
16:55JTR
Lufthansa, Discover Airlines
20:45JTR
13h 35m1 stop
09:20MAD
SWISS
from£276

Explore all offers

Direct flights from Madrid to Santorini

Book direct flights from Madrid to Santorini for a smooth journey.

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Flights from Madrid to Santorini one way

Find one-way flights from Madrid to Santorini at great prices.

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Iberia flights from Madrid to Santorini

Fly with Iberia from Madrid to Santorini for less.

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Flights to Santorini with top airlines

IberiaCheapest
from £333.99

Madrid to Santorini flight information

DEPARTING FROM:

Adolfo Suarez Madrid-Barajas Airport

ARRIVING IN:

Santorini International Airport

AIRLINES:

Iberia

AVG FLIGHT TIME:

3h 40m

More information about flights to Santorini from Madrid

Information about flights from Madrid to Santorini

Once you have your flight Madrid-Santorini booked you can always use lastminute.com to organise the rest of your trip just the way you want it. lastminute.com allows you to book a hotel, car hire, tours and activities in Santorini.

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Madrid to Santorini , all you have to do is complete the search form and in no time you will be flying off to Santorini.

When you’re looking to get away and not interested in a precise date, take a look at our flight offers this month. Flight deals from Madrid to Santorini are great time of year. Be inspired!

Low cost flights to Santorini from Madrid are not always easy to find. lastminute.com wants to make it easy for you to find a inexpensive option, so with us you can even choose flights with different airlines and save money on your next trip .

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

FAQs Madrid to Santorini flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Madrid and Santorini?
The flight from Madrid to Santorini has a duration of 3h 40m.
What are the cheapest flights from Madrid to Santorini?
The cheapest one-way flight costs £64 flying with Iberia and the cheapest return flight costs £372 with Iberia.
How many airports are there in the city of Madrid?
Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.
How many airports does Santorini have?
There are 1 airports in Santorini: Santorini International Airport
Which Santorini airport is the most central?
The most central airport is Santorini International Airport, 4.2km.
Which airlines have flights from Madrid to Santorini?
There are 1 airlines with flights from Madrid to Santorini; Those that offer lower prices are Iberia (£64).
Schedules of the first and last flight from Madrid to Santorini
The first flight from Madrid to Santorini is at 14:45 and the last flight departs at 22:50.

Iberia cheap flights