Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Madrid and Santo Domingo?

The flight from Madrid to Santo Domingo has a duration of 9h 3m.

What are the cheapest flights from Madrid to Santo Domingo?

The cheapest one-way flight costs £289 flying with WORLD2FLY and the cheapest return flight costs £487 with WORLD2FLY.

How many airports are there in the city of Madrid?

Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.

How many airports does Santo Domingo have?

There are 1 airports in Santo Domingo: Las Americas Airport

Which Santo Domingo airport is the most central?

The most central airport is Las Americas Airport, 23.9km.

Which airlines have flights from Madrid to Santo Domingo?

There are 3 airlines with flights from Madrid to Santo Domingo; Those that offer lower prices are WORLD2FLY (£264), Air Europa (£329), Iberia (£791).

Schedules of the first and last flight from Madrid to Santo Domingo

The first flight from Madrid to Santo Domingo is at 13:45 and the last flight departs at 18:50.

Cheap flights from Madrid to Santo Domingo

Fly smart, spend less

Flights to Santo Domingo from Madrid

Cheap flights from Madrid to Santo Domingo from £289. Madrid (Spain) - Santo Domingo (Dominican Republic) return flights from £487. From 18/10/2026 (Sunday) - 23/10/2026 (Friday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Madrid to Santo Domingo

Cheapest round-trip flights from Madrid to Santo Domingo

29 Nov - 08 Dec • 9 nights
09:15MAD
9h 35mDirect
13:50SDQ
Iberia
15:20SDQ
8h 30mDirect
04:50MAD
Iberia
from£476
15 Nov - 19 Nov • 4 nights
16:20MAD
9h 15mDirect
20:35SDQ
WORLD2FLY
23:05SDQ
8h 20mDirect
12:25MAD
WORLD2FLY
from£487
19 Nov - 29 Nov • 10 nights
16:20MAD
9h 15mDirect
20:35SDQ
WORLD2FLY
23:05SDQ
8h 20mDirect
12:25MAD
WORLD2FLY
from£487
26 Nov - 06 Dec • 10 nights
16:20MAD
9h 15mDirect
20:35SDQ
WORLD2FLY
23:05SDQ
8h 20mDirect
12:25MAD
WORLD2FLY
from£487
19 Nov - 29 Nov • 10 nights
16:15MAD
9h 15mDirect
20:30SDQ
Iberia
15:20SDQ
8h 30mDirect
04:50MAD
Iberia
from£493
21 Nov - 30 Nov • 9 nights
16:15MAD
9h 15mDirect
20:30SDQ
Iberia
15:20SDQ
8h 30mDirect
04:50MAD
Iberia
from£493

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Direct flights from Madrid to Santo Domingo

Book direct flights from Madrid to Santo Domingo for a smooth journey.

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Flights from Madrid to Santo Domingo one way

Find one-way flights from Madrid to Santo Domingo at great prices.

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Iberia flights from Madrid to Santo Domingo

Fly with Iberia from Madrid to Santo Domingo for less.

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Flights to Santo Domingo with top airlines

Iberia
from £509.99
Air EuropaCheapest
from £505.99

Madrid to Santo Domingo flight information

DEPARTING FROM:

Adolfo Suarez Madrid-Barajas Airport

ARRIVING IN:

Las Americas Airport

AIRLINES:

Air Europa, Iberia, WORLD2FLY

AVG FLIGHT TIME:

9h 3m

More information about flights to Santo Domingo from Madrid

Information about flights from Madrid to Santo Domingo

Once you have your flight Madrid-Santo Domingo booked you can always use lastminute.com to organise the rest of your trip just the way you want it. lastminute.com allows you to book a hotel, car hire, tours and activities in Santo Domingo.

lastminute.com would like to be the perfect travel tool for all your travelling needs . The lastminute.com App is also available for the smartphone so you don’t miss out and being able to use our search engine from wherever you are.

Not only can you use the lastminute.com website to search low cost flights, but we have even preselected some flight offers from Madrid to Santo Domingo for you to save you time.

Need inspiration for your next holiday? Join lastminute.com’s facebook page and be sure to get top travel tips for your next trip .

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Madrid to Santo Domingo , all you have to do is complete the search form and in no time you will be flying off to Santo Domingo.

FAQs Madrid to Santo Domingo flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Madrid and Santo Domingo?
The flight from Madrid to Santo Domingo has a duration of 9h 3m.
What are the cheapest flights from Madrid to Santo Domingo?
The cheapest one-way flight costs £289 flying with WORLD2FLY and the cheapest return flight costs £487 with WORLD2FLY.
How many airports are there in the city of Madrid?
Madrid has 1 airport: Adolfo Suarez Madrid-Barajas Airport.
How many airports does Santo Domingo have?
There are 1 airports in Santo Domingo: Las Americas Airport
Which Santo Domingo airport is the most central?
The most central airport is Las Americas Airport, 23.9km.
Which airlines have flights from Madrid to Santo Domingo?
There are 3 airlines with flights from Madrid to Santo Domingo; Those that offer lower prices are WORLD2FLY (£264), Air Europa (£329), Iberia (£791).
Schedules of the first and last flight from Madrid to Santo Domingo
The first flight from Madrid to Santo Domingo is at 13:45 and the last flight departs at 18:50.

Cheap flights London - Santo Domingo