Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How long does a flight take between Brussels and Madrid?

The flight from Brussels to Madrid has a duration of 2h 26m.

What are the cheapest flights from Brussels to Madrid?

The cheapest one-way flight costs £65 flying with Brussels Airlines and the cheapest return flight costs £116 with Air Europa.

How many airports are there in the city of Brussels?

Brussels has 2 airport: Charleroi Airport, Brussels Airport.

How many airports does Madrid have?

There are 1 airports in Madrid: Adolfo Suarez Madrid-Barajas Airport

Which Madrid airport is the most central?

The most central airport is Adolfo Suarez Madrid-Barajas Airport, 12.8km.

Which airlines have flights from Brussels to Madrid?

There are 4 airlines with flights from Brussels to Madrid; Those that offer lower prices are Iberia (£86), Brussels Airlines (£111), Air Europa (£115).

Schedules of the first and last flight from Brussels to Madrid

The first flight from Brussels to Madrid is at 09:35 and the last flight departs at 23:25.

Cheap flights from Brussels to Madrid

Fly smart, spend less

Flights to Madrid from Brussels

Cheap flights from Brussels to Madrid from £65. Brussels (Belgium) - Madrid (Spain) return flights from £116. From 05/12/2026 (Saturday) - 08/12/2026 (Tuesday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Brussels to Madrid

Cheapest round-trip flights from Brussels to Madrid

08 Nov - 10 Nov • 2 nights
21:00BRU
2h 30mDirect
23:30MAD
Brussels Airlines
06:25MAD
2h 25mDirect
08:50BRU
Brussels Airlines
from£107
08 Nov - 10 Nov • 2 nights
21:00BRU
2h 30mDirect
23:30MAD
Brussels Airlines
12:35MAD
2h 15mDirect
14:50BRU
Brussels Airlines
from£115
05 Dec - 08 Dec • 3 nights
10:45BRU
2h 30mDirect
13:15MAD
Air Europa
07:20MAD
2h 30mDirect
09:50BRU
Air Europa
from£116
05 Dec - 08 Dec • 3 nights
10:45BRU
2h 30mDirect
13:15MAD
Air Europa
15:15MAD
2h 30mDirect
17:45BRU
Air Europa
from£116
08 Nov - 10 Nov • 2 nights
17:25BRU
2h 30mDirect
19:55MAD
Brussels Airlines
06:25MAD
2h 25mDirect
08:50BRU
Brussels Airlines
from£119
05 Dec - 08 Dec • 3 nights
09:20BRU
2h 25mDirect
11:45MAD
Brussels Airlines
12:35MAD
2h 15mDirect
14:50BRU
Brussels Airlines
from£120

Explore all offers

Direct flights from Brussels to Madrid

Book direct flights from Brussels to Madrid for a smooth journey.

Explore all offers

Flights from Brussels to Madrid one way

Find one-way flights from Brussels to Madrid at great prices.

Explore all offers

Iberia flights from Brussels to Madrid

Fly with Iberia from Brussels to Madrid for less.

Explore all offers

Brussels to Madrid flight information

DEPARTING FROM:

Brussels Airport, Charleroi Airport

ARRIVING IN:

Adolfo Suarez Madrid-Barajas Airport

AIRLINES:

Air Europa, Brussels Airlines, Iberia, Ryanair

AVG FLIGHT TIME:

2h 26m

More information about flights to Madrid from Brussels

Information about flights from Brussels to Madrid

Once you have your flight Brussels-Madrid booked you can always use lastminute.com to organise the rest of your trip just the way you want it. lastminute.com allows you to book a hotel, car hire, tours and activities in Madrid.

Join lastminute.com’s facebook page and be informed on the latest travel giveaways and news. Make your trip a memorable one and then tell us about it!

When you’re looking to get away and not interested in a precise date, take a look at our flight offers this month. Flight deals from Brussels to Madrid are great time of year. Be inspired!

If you are a frequent traveller , download our iPhone and Android app free of charge. It will change your travelling habits and be extremely useful whilst you are away on trips.

Hi and welcome to your perfect solution to finding low cost flights in just a few clicks! When searching for a low cost flight from Brussels to Madrid , all you have to do is complete the search form and in no time you will be flying off to Madrid.

FAQs Brussels to Madrid flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
How long does a flight take between Brussels and Madrid?
The flight from Brussels to Madrid has a duration of 2h 26m.
What are the cheapest flights from Brussels to Madrid?
The cheapest one-way flight costs £65 flying with Brussels Airlines and the cheapest return flight costs £116 with Air Europa.
How many airports are there in the city of Brussels?
Brussels has 2 airport: Charleroi Airport, Brussels Airport.
How many airports does Madrid have?
There are 1 airports in Madrid: Adolfo Suarez Madrid-Barajas Airport
Which Madrid airport is the most central?
The most central airport is Adolfo Suarez Madrid-Barajas Airport, 12.8km.
Which airlines have flights from Brussels to Madrid?
There are 4 airlines with flights from Brussels to Madrid; Those that offer lower prices are Iberia (£86), Brussels Airlines (£111), Air Europa (£115).
Schedules of the first and last flight from Brussels to Madrid
The first flight from Brussels to Madrid is at 09:35 and the last flight departs at 23:25.