Can I combine different airlines on the same trip?

Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What options are there if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.**Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.****Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

What are the cheapest flights from Brindisi to Rome?

The cheapest one-way flight costs £30 flying with Ryanair and the cheapest return flight costs £96 with AccesRail.

How many airports are there in the city of Brindisi?

Brindisi has 2 airport: Brindisi - Salento Airport, Bari Karol Wojtyla Airport.

How many airports does Rome have?

There are 3 airports in Rome: ROM - All airports, Fiumicino Airport, Rome Ciampino Airport

Which Rome airport is the most central?

The most central airport is ROM - All airports, 12.8km.

Which airlines have flights from Brindisi to Rome?

There are 4 airlines with flights from Brindisi to Rome; Those that offer lower prices are AccesRail (£81), ITA Airways (£132), Ryanair (£99).

Schedules of the first and last flight from Brindisi to Rome

The first flight from Brindisi to Rome is at 07:35 and the last flight departs at 01:00.

Cheap flights from Brindisi to Rome

Fly smart, spend less

Flights to Rome from Brindisi

Cheap flights from Brindisi to Rome from £30. Brindisi (Italy) - Rome (Italy) return flights from £96. From 14/09/2026 (Monday) - 16/09/2026 (Wednesday). Check for the dates with the lowest prices and find the cheapest rates.

Round-trip flights from Ostuni to Rome

Cheapest round-trip flights from Ostuni to Rome

02 Oct - 05 Oct • 3 nights
23:40BDS
1h 20mDirect
01:00FCO
Ryanair
05:45FCO
1h 15mDirect
07:00BDS
Ryanair
from£44
07 Oct - 15 Oct • 8 nights
07:30BDS
1h 20mDirect
08:50FCO
Ryanair
05:50FCO
1h 15mDirect
07:05BDS
Ryanair
from£52
07 Oct - 15 Oct • 8 nights
17:50BDS
1h 20mDirect
19:10FCO
Ryanair
05:50FCO
1h 15mDirect
07:05BDS
Ryanair
from£55
02 Oct - 05 Oct • 3 nights
16:25BDS
1h 20mDirect
17:45FCO
Ryanair
05:45FCO
1h 15mDirect
07:00BDS
Ryanair
from£56
07 Oct - 15 Oct • 8 nights
07:30BDS
1h 20mDirect
08:50FCO
Ryanair
15:25FCO
1h 15mDirect
16:40BDS
Ryanair
from£92
07 Oct - 15 Oct • 8 nights
17:50BDS
1h 20mDirect
19:10FCO
Ryanair
15:25FCO
1h 15mDirect
16:40BDS
Ryanair
from£96

Explore all offers

Direct flights from Ostuni to Rome

Book direct flights from Ostuni to Rome for a smooth journey.

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Flights from Ostuni to Rome one way

Find one-way flights from Ostuni to Rome at great prices.

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Cheap flights from Brindisi - Salento Airport to Rome

Find cheap flights from Brindisi - Salento Airport to Rome now.

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Cheap flights from Bari Karol Wojtyla Airport to Rome

Find cheap flights from Bari Karol Wojtyla Airport to Rome now.

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More information about flights to Rome from Brindisi

Information about flights from Brindisi to Rome

Low cost flights to Rome from Brindisi are not always easy to find. lastminute.com wants to make it easy for you to find a inexpensive option, so with us you can even choose flights with different airlines and save money on your next trip .

If you are a frequent traveller , lastminute.com would like to be your trusted one stop travel partner in helping you find flights, hotels and car hire in Rome and worldwide.

lastminute.com selects from hundreds of flight deals Brindisi-Rome some of the best deals that month to save you time. Why not take advantage of the monthly flight offers and book now.

Once your flight Brindisi-Rome is booked, using lastminute.com you can even organise the rest of your trip. From car hire and accommodation in Rome as well as a guide to Rome so you know in advance what there is to see and do.

lastminute.com’s flight search finds you all available low cost flights from Brindisi to Rome in just a few clicks. When looking for a low cost flight Brindisi-Rome, simply specify departure and arrival dates and the maximum price you want to pay. It’s that simple!

FAQs Brindisi to Rome flights

FAQs

Can I combine different airlines on the same trip?
Of course. We offer you the possibility of booking with more than 400 airlines so that you can find the cheapest fare or the most convenient combination: outbound flight with one airline and return flight with another.
Is lastminute.com a trustworthy travel brand?
In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.
What options are there if I have to change my flight?
lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*
*Flexibility services are available on selected flights only. Please read our T&Cs for more information.
I am afraid to lose my luggage, every time I fly. What can I do?
lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**
**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.
What are the cheapest flights from Brindisi to Rome?
The cheapest one-way flight costs £30 flying with Ryanair and the cheapest return flight costs £96 with AccesRail.
How many airports are there in the city of Brindisi?
Brindisi has 2 airport: Brindisi - Salento Airport, Bari Karol Wojtyla Airport.
How many airports does Rome have?
There are 3 airports in Rome: ROM - All airports, Fiumicino Airport, Rome Ciampino Airport
Which Rome airport is the most central?
The most central airport is ROM - All airports, 12.8km.
Which airlines have flights from Brindisi to Rome?
There are 4 airlines with flights from Brindisi to Rome; Those that offer lower prices are AccesRail (£81), ITA Airways (£132), Ryanair (£99).
Schedules of the first and last flight from Brindisi to Rome
The first flight from Brindisi to Rome is at 07:35 and the last flight departs at 01:00.