5 star accommodation in Panama 2026/2027

Panama 5-star hotels

For a mix of modern city luxury and beachfront relaxation, 5-star hotels in Panama offer elegant high-rises in Panama City, boutique resorts in Bocas del Toro, and private island escapes. Enjoy world-class service and breathtaking scenery.

Best deals on Five star hotels in Panama

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Hotel
Riu Plaza Panama
rated as 4 out of 5 by 5,139 reviewers
1.12 mi from city centre
from £158 per night
Hotel
Hyatt Regency Panama City
rated as 4.5 out of 5 by 141 reviewers
5,125 ft from city centre
from £175 per night
Hotel
Megapolis Hotel Panama
rated as 3.5 out of 5 by 325 reviewers
1.19 mi from city centre
from £136 per night
Resort
Hotel Riu Playa Blanca - All Inclusive
rated as 4 out of 5 by 5,884 reviewers
2.22 mi from city centre
from £218 per night
Hotel
Sofitel Legend Casco Viejo, Panama City
rated as 5 out of 5 by 654 reviewers
1.37 mi from city centre
Hotel
Gran Evenia Panamá Hotel
rated as 4 out of 5 by 51 reviewers
1 mi from city centre
Hotel
Bristol Panama, a Registry Collection Hotel
rated as 4.5 out of 5 by 1,987 reviewers
4,692 ft from city centre
from £163 per night
Hotel
La Coralina Island House
rated as 4 out of 5 by 142 reviewers
2.4 mi from city centre
Resort
Gran Evenia Bijao - All Inclusive
rated as 4 out of 5 by 196 reviewers
6.57 mi from city centre
from £154 per night
Country house
Central Hotel Bocas del Toro
rated as 5 out of 5 by 16 reviewers
9.74 mi from city centre
Hotel
Sansara Surf Yoga & Resort
rated as 5 out of 5 by 445 reviewers
1.56 mi from city centre
B&B
The Hummingbird
rated as 5 out of 5 by 207 reviewers
4.26 mi from city centre
Resort
Nayara Bocas del Toro
rated as 5 out of 5 by 234 reviewers
7.14 mi from city centre
Hotel
Hotel La Compañía Casco Antiguo
rated as 5 out of 5 by 834 reviewers
1.35 mi from city centre
from £624 per night
Hotel
Hotel La Compania Del Valle
rated as 5 out of 5 by 155 reviewers
4,439 ft from city centre

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Luxury hotels in Panama: 5-star stays in Central America’s modern hub

Panama, a country of soaring skyscrapers, lush rainforests, and stunning coastlines, offers luxurious city hotels, high-end beachfront resorts, and elegant eco-lodges. Whether in Panama City’s bustling streets or the pristine Pearl Islands, Panama is a sophisticated luxury destination.

Where to stay: the best areas for 5-star hotels in Panama

Stay in Casco Viejo for historic elegance, Punta Pacifica for ultra-modern high-rises, or Bocas del Toro for private island retreats.

What to expect from 5-star hotels in Panama

Expect oceanfront infinity pools, fine Latin American dining, premium wellness retreats, and tropical luxury. Many hotels offer VIP rainforest excursions, private canal tours, and curated island-hopping experiences.

Five star hotels in Panama

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Five star hotels Panama City