5-star hotels - which are nearest to the main local attractions in Panama City?

Panama Viejo:Ancon Hill: Hotel La Compañía Casco Antiguo, Sofitel Legend Casco Viejo, Panama City, Hotel Bardot BoutiquePanama Canal Railway:

5-star hotels in Panama City 2026/2027

Panama City 5-star hotels

Blending modern skyscrapers with colonial charm, 5-star hotels in Panama City include luxury waterfront stays, boutique Casco Viejo retreats, and stylish urban escapes. Enjoy warm hospitality and stunning city views.

Best 5-star hotels deals in Panama City

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Hotel
Riu Plaza Panama
rated as 4 out of 5 by 5,106 reviewers
1,594 ft from city centre
from £122 per night
Hotel
Megapolis Hotel Panama
rated as 3.5 out of 5 by 323 reviewers
3,176 ft from city centre
from £133 per night
Hotel
Sofitel Legend Casco Viejo, Panama City
rated as 5 out of 5 by 638 reviewers
2.11 mi from city centre
from £479 per night
Hotel
Gran Evenia Panamá Hotel
rated as 4 out of 5 by 51 reviewers
1,647 ft from city centre
Hotel
Bristol Panama, a Registry Collection Hotel
rated as 4.5 out of 5 by 1,983 reviewers
266 ft from city centre
from £130 per night
Hotel
Hotel La Compañía Casco Antiguo
rated as 5 out of 5 by 817 reviewers
2.15 mi from city centre
from £658 per night
Hotel
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
rated as 4.5 out of 5 by 520 reviewers
5.77 mi from city centre
from £260 per night
Hotel
Hyatt Regency Panama City
rated as 4.5 out of 5 by 134 reviewers
400 ft from city centre
from £98 per night
Hotel
Global Hotel Panama
rated as 4.5 out of 5 by 841 reviewers
2,018 ft from city centre
Hotel
Hilton Panama
rated as 4.5 out of 5 by 2,577 reviewers
2,126 ft from city centre
from £273 per night
Hotel
Renaissance Panama City Hotel
rated as 4.5 out of 5 by 35 reviewers
725 ft from city centre
from £146 per night
Hotel
Waldorf Astoria Panama
rated as 4.5 out of 5 by 2,446 reviewers
1,670 ft from city centre
from £328 per night
Hotel
JW Marriott Panama
rated as 4 out of 5 by 2,837 reviewers
1.34 mi from city centre
from £347 per night
Hotel
W Panama
rated as 4 out of 5 by 439 reviewers
617 ft from city centre
Hotel
Sheraton Grand Panama
rated as 4 out of 5 by 961 reviewers
1.73 mi from city centre
from £153 per night

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Luxury hotels in Panama City: 5-star stays in Central America’s cosmopolitan hub

Panama City, a modern metropolis with a blend of colonial charm and cutting-edge luxury, offers high-end city hotels, boutique waterfront retreats, and exclusive rainforest resorts. Whether in Casco Viejo’s historic streets or the skyline of Punta Pacifica, Panama City is a sophisticated luxury destination.

Where to stay: the best areas for 5-star hotels in Panama City

Stay in Casco Viejo for colonial elegance, Punta Pacifica for ultra-modern high-end hotels, or Amador Causeway for boutique waterfront stays.

What to expect from 5-star hotels in Panama City

Expect skyline infinity pools, gourmet Latin American cuisine, world-class spa facilities, and stunning Pacific Ocean views. Many hotels offer private yacht rentals, VIP rainforest excursions, and exclusive canal tours.

FAQs

5-star hotels - which are nearest to the main local attractions in Panama City?
Panama Viejo:
Ancon Hill: Hotel La Compañía Casco Antiguo, Sofitel Legend Casco Viejo, Panama City, Hotel Bardot Boutique
Panama Canal Railway:

Nearby holiday destinations

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