Flights from Chicago to Saint Louis from £114

Check out our best offers departing from Chicago among more than 400 airlines now!

Change departure

Use the search-box to select your departure city or airport and get the best prices. Please, note these prices below are 'from'.

Prices refer to lowest available return flight, and are per person for the dates shown. The flights are subject to seat availability as well as variations in the price and tariffs.

Information about flights from Chicago to Saint Louis

Not only can you use the lastminute.com website to search low cost flights, but we have even preselected some flight offers from Chicago to Saint Louis for you to save you time.

Join lastminute.com’s facebook page and be informed on the latest travel giveaways and news. Make your trip a memorable one and then tell us about it!

What could be easier than using lastminute.com as your one stop travel shop? With all the services you find on lastminute.com, it’s more than just flights, you can book all the travel requirements for you trips right here.

Looking for low cost flights from Chicago to Saint Louis? Then look no further… lastminute.com searches all available flights from Chicago to Saint Louis from amongst the top low cost and scheduled airlines.

Explore the additional services available on lastminute.com even once you have booked your flight Chicago-Saint Louis. On lastminute.com, as well as your flight Chicago-Saint Louis, you can also book car hire, ready for you on arrival in Saint Louis. If you want to stay in Saint Louis, our website has also created a way for you to book a hotel room in Saint Louis with no fuss.

Maybe you are interested in Cheap flights to Chicago Nows your chance!

Cheap flights from United Kingdom cities to Saint Louis

Cheap flights London - Saint Louis
Departing on Monday, 13 September 2021 and returning on Saturday, 18 September 2021

from £813

31d ago
Cheap flights Manchester - Saint Louis
Departing on Friday, 10 September 2021 and returning on Tuesday, 14 September 2021

from £794

35d ago

Frequently asked questions

How do I buy tickets from different airlines at once and save money?

Our system combines airlines automatically to find the cheapest flights available. That way you can save money and don't have to buy your tickets separately.

Is lastminute.com a trustworthy travel brand?

In 1998, lastminute.com was one of the first online travel agencies. Currently, we are selling over 380,000 flights per year – and working hard on bringing travellers wherever they want to go.

What should I do if I have to change my flight?

lastminute.com offers flexibility services for purchase at the time of your booking. These services entitle you to change or cancel your flights without handling fee.*

*Flexibility services are available on selected flights only. Please read our T&Cs for more information.

I am afraid to lose my luggage, every time I fly. What can I do?

lastminute.com offers a range of baggage protection services, so that you are covered in case your luggage is delayed or lost.**

**Baggage protection services are available on selected flights only. Please read our T&Cs for more information.

How far is Saint Louis from Chicago by plane?

Between Saint Louis and Chicago lie approximately 422 miles.

How many airports does Chicago have?

There are 2 airports in Chicago: Chicago Midway and Chicago O'Hare.

How many airports does Saint Louis have?

There are 3 airports in Saint Louis: Saint Louis, Saint Louis USA and Saint Louis.

What is the nearest airport to Saint Louis's city centre?

Saint Louis USA is 19 miles from the city center while Saint Louis is 20 miles away

What is the average cost of a taxi in Chicago? and in Saint Louis?

In Saint Louis, a taxi ride costs about £2.00, in Chicago it costs about £3.00.

How much does a single ticket for the public transport in Saint Louis cost? How much does it cost in Chicago?

A single ticket in Saint Louis costs at least of £2.00. In Chicago, it is at least £2.00.

Cost of living in Chicago compared with Saint Louis

Food and drinks	Chicago	Saint Louis	Difference
Beer (0.5 litre)	£2.00	£2.00	0%
Coffee	£3.00	£3.00	0%
Meal at McDonald's	£6.00	£6.00	0%
Water (0.33 litre)	£1.00	£1.00	0%
Transportation	Chicago	Saint Louis	Difference
Monthly pass	£86.00	£57.00	-34%
One way tube ticket	£2.00	£2.00	0%
Taxi starting price (normal tariff)	£3.00	£2.00	-33%
Clothing	Chicago	Saint Louis	Difference
1 summer dress in a chain store (Zara, H&M,...)	£32.00	£27.00	-16%
1 pair of jeans (Levi's 501 or similar)	£43.00	£36.00	-16%
Salaries	Chicago	Saint Louis	Difference
Average monthly disposable salary (net)	£3,321.00	£2,663.00	-20%